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 SUPERHUMAN - using virus to combat cancer and aids
             


           

Robert Winston's SUPERHUMAN ABC TV Thursday 1.00 PM

Injecting a virus directly into the cancer tuma stunted growth.

Robert Swan was the first • drilled a hole and injected direct into the brain/tuma herpes simplex - the same virus that causes cold sores - it's particularly effective at destroying rapidly dividing cells.

Prof. Moira Brown
Glasgow Southern General Hospital

"In the brain most of the cells are no longer diving - so could this be used as a therapeutic tool?"

4 years later - It hasn't shrunk but it has stopped growing - he has checkups with Dr Ramplings - scans show tuma is static and no sign the virus has escaped to do any harm.
http://www.gla.ac.uk/clinicalneuroscience/staffbrown.html
University of Glasgow




www.thenakedscientists.com
Professor Moira Brown is a virologist at Glasgow University, where she has developed a strain of herpes virus (strain 1716) which only replicates (grows) in rapidly dividing cells, including cancerous cells. This genetically modified virus can be injected into brain tumours, where it grows, killing the cancer cells. But when the virus reaches the edge of the tumour and healthy brain tissue, which does not contain rapidly dividing cells, the virus stops growing. Moira's team are now also investigating the potential of this type of therapy in other types of tumours elsewhere on the body, including malignant melanoma.


A herpes simplex virus, as seen under the electron microscope. The outer (white) layer is the viral envelope. The nucleo-capsid (the central white 'core') contains the viral DNA. http://www.thenakedscientists.com/index.htm?HTML/Guestfile/moirabrown.htm~mainFrame




CRUSADE LABORATORIES
HSV1716 in head and neck cancer

The most common type of malignant tumour in the head and neck region is squamous cell carcinoma. Squamous cells make up the linings of the mouth, nose and throat.

A Phase II trial in 20 patients with squamous cell carcinoma of the head and neck started in March 2002. Recruitment of patients for this trial is in progress.

The clinical trials are carried out at the Institute of Neurological Sciences (INS) at the Southern General Hospital.



CLICK HERE to SEARCH for "Moira Brown HSV1716"
IN GOOGLE
http://www.google.com/search?q=Moira+Brown+HSV1716&ie=UTF-8&oe=UTF-8



GERM WARFARE
Not all bacteria are bad, and some diseases can even help to defeat others. Killers into Cures meets Robert Swan, who volunteered to have the herpes virus injected into his brain in a bold bid to halt the growth of an inoperable tumour. Four years on, the results have been remarkable. ...more



"Engineering Reproduction: Will We Still Be Human At The End of the 21st Century"


by Professor Lord Robert Winston
Capitol Theatre
Sunday, May 13, 2001, 6pm

http://www.abc.net.au/rn/deakin/stories/s291481.htm



HIV/AIDS infection…
HIV (Human Immunodeficiency virus) is cause of Aids and was discovered 20 years ago. There are over 42 million sufferers of HIV worldwide and infects the CD4 T cells (chiefs of the immune system) where they kill and stop them from working properly. These cells replace themselves and eventually the virus overwhelms the immune system. Treatment had started for Aids in 1981, HIV in 1983 and the A2T drug was developed in 1987 to treat the HIV virus. From 1996 the triple therapy was the standard therapy. However these 3 classes of drugs is not considered a cure - simply for the reasons that the drugs have to be taken forever, and not all sufferers have equal access to it and the treatment can be ineffective if missed on occasions. A major issue concerning the HIV virus is that it is hardly recognizable. The HIV virus is coated with sugar molecules and triggers to produce the wrong antibodies; this integrates into the human DNA and cannot be recognized very well.
http://www.lboro.ac.uk/admin/committees/prizes/02-03/leb/03leb.htm


SUPERHUMAN BOOK
             


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